Evaluation of the Sensitivity of USP Prednisone Tablets to Dissolved Gas in the Dissolution Medium Using USP Apparatus 2
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چکیده
منابع مشابه
Suppository Dissolution Utilizing USP Apparatus
Standardized in-vitro dissolution testing of suppositories has been of interest to the pharmaceutical industry since the early works of Giabaldi and Gundhofer in 1975.(1) Anthony Palmieri exam ined standard izin g suppository dissolutions in his work at the University of Wyoming (2). Palmieri developed a slotted dissolution basket for suppositories that is ---------widely used by many individua...
متن کاملCalibration—the Usp Dissolution Apparatus Suitability Test
This report summarizes some trends observed in drug dissolution testing, based upon the United States Pharmacopeia (USP) dissolution Apparatus Suitability Test results and the preliminary data obtained from an international collaborative study to assess the pharmaceutical quality of furosemide products in different countries. Based on the USP calibrator data submitted by the participants, repre...
متن کاملInvestigation of the Dissolution Characteristics of Nifedipine Extended-Release Formulations Using USP Apparatus 2 and a Novel Dissolution Apparatus
INTRODUCTION Nifedipine is a calcium-channel blocking agent that is widely used in the treatment of angina pectoris and systemic hypertension (1). The pharmacokinetics and pharmacodynamics of nifedipine have been investigated in numerous studies (2–4). Clinical experiences gained with oral nifedipine formulations with immediate-release (IR) characteristics clearly show that a steep rise in the ...
متن کاملThe importance of boundary conditions in the simulation of dissolution in the USP dissolution apparatus
As shown in previous papers, mathematical simulation can be useful in the design of drug delivery systems. We present a finite-difference approximation to the drug mass transfer rate from dissolving cylindrical drug-containing compacts, consisting of alternating layers of drug and inert material. Results are compared with a recent analytical solution to the same problem and with experiment. The...
متن کاملShort Communication EVALUATION OF USP BASKET AND PADDLE DISSOLUTION METHODS USING DIFFERENT GENERIC ATENOLOL TABLETS
Atenolol is a widely used drug for treating heart conditions available worldwide under various trade names by several generic pharmaceutical manufacturers. The purpose of this study was to evaluate and compare the dissolution performance of several commercially available generic atenolol tablets using both basket and paddle methods described in the United States Pharmacopeia-National Formulary ...
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ژورنال
عنوان ژورنال: Dissolution Technologies
سال: 2006
ISSN: 1521-298X
DOI: 10.14227/dt130306p15